Leigh syndrome: MRI findings in two children

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Leigh syndrome: MRI findings in two children

Leigh syndrome is a progressive neurodegenerative disorder of childhood. The symmetrical necrotic lesions in the basal ganglia and/or brainstem which appear as hyperintense lesions on T2-weighted MRI is characteristic and one of the essential diagnostic criteria. Recognising this MR imaging pattern in a child with neurological problems should prompt the clinician to investigate for Leigh syndro...

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A 10 years old girl, was admitted to the intensive care unit with seizure, myotonic-clonic jerks in her hands, vomiting, respiratory failure and mild metabolic acidosis. Brain Magnetic resonance imaging (MRI) and proton MR spectroscopy(MRS) were performed.The MRI findings presented symmetric basal ganglia, brain stem, left thalamus and subthalamic nuclei involvement. MRS obtained from the basal...

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ژورنال

عنوان ژورنال: Biomedical Imaging and Intervention Journal

سال: 2010

ISSN: 1823-5530

DOI: 10.2349/biij.6.1.e6